Hydroxyl Surface and Nucleic Acid Binding
Silanol groups on the silica surface participate in nucleic acid adsorption. Binding and elution performance must be matched to the buffer system, sample type and experimental workflow.
SCI MATERIALS HUB · FUNCTIONAL MAGNETIC MICROSPHERES
Hydroxyl-Functionalized Silica Magnetic Beads
SiO₂ hydroxyl magnetic beads are silica magnetic microspheres with surface hydroxyl groups, supplied as a dispersion in ultrapure water for nucleic acid extraction and purification research. Nucleic acids bind under compatible binding-buffer conditions and are separated and recovered through magnetic separation, washing and elution. This page offers five particle sizes from 150 to 500nm, each available in 5mL and 10mL packs at a concentration of 10mg/mL.
Select the particle size and pack volume for your experiment. All variants have a concentration of 10mg/mL.
| Product | SiO₂ Hydroxyl Magnetic Beads | Matrix | Silica magnetic microspheres |
|---|---|---|---|
| Surface | Hydroxyl groups (silanol, –Si–OH) | Form | Dispersion in ultrapure water |
| Diameter | 150, 200, 300, 400, 500nm | Conc. | 10mg/mL |
| Pack Size | 5mL, 10mL | Variants | 10 variants, listed individually |
| Storage | 2–25°C | Shelf Life | 360 days; refer to the bottle label for the expiry date |
| Uses | Nucleic acid extraction and purification research | Currency | USD per pack; whole-dollar retail prices |
Silanol groups on the silica surface participate in nucleic acid adsorption. Binding and elution performance must be matched to the buffer system, sample type and experimental workflow.
After binding, magnetic separation collects the beads for supernatant removal, washing and elution in magnetic-bead-based nucleic acid extraction and purification research.
All five particle sizes are available in 5mL and 10mL packs. Select a suitable size and pack volume according to your experimental consumption, magnetic separation conditions and mixing method.
| Product Specification | Diameter | Pack Size | Retail (USD) |
|---|---|---|---|
| SiO2_Hydroxyl_Magnetic_Beads_150nm_5mL_10mg/mL | 150nm | 5mL | $63 |
| SiO2_Hydroxyl_Magnetic_Beads_150nm_10mL_10mg/mL | 150nm | 10mL | $113 |
| SiO2_Hydroxyl_Magnetic_Beads_200nm_5mL_10mg/mL | 200nm | 5mL | $63 |
| SiO2_Hydroxyl_Magnetic_Beads_200nm_10mL_10mg/mL | 200nm | 10mL | $113 |
| SiO2_Hydroxyl_Magnetic_Beads_300nm_5mL_10mg/mL | 300nm | 5mL | $63 |
| SiO2_Hydroxyl_Magnetic_Beads_300nm_10mL_10mg/mL | 300nm | 10mL | $113 |
| SiO2_Hydroxyl_Magnetic_Beads_400nm_5mL_10mg/mL | 400nm | 5mL | $63 |
| SiO2_Hydroxyl_Magnetic_Beads_400nm_10mL_10mg/mL | 400nm | 10mL | $113 |
| SiO2_Hydroxyl_Magnetic_Beads_500nm_5mL_10mg/mL | 500nm | 5mL | $63 |
| SiO2_Hydroxyl_Magnetic_Beads_500nm_10mL_10mg/mL | 500nm | 10mL | $113 |
Please provide the complete specification and quantity when ordering. Example: SiO2_Hydroxyl_Magnetic_Beads_200nm_5mL_10mg/mL, quantity: 2 packs.
The following outlines the basic magnetic-bead-based nucleic acid extraction workflow. Use the reagents, quantities and operating conditions specified by your selected extraction protocol.
Lyse the sample according to the sample-preparation protocol to release its nucleic acids.
Allow the released nucleic acids to bind to the beads under compatible binding-buffer conditions.
Collect the beads by magnetic separation and wash according to the protocol to remove impurities.
Complete the drying step specified in the extraction protocol to address residual wash solution on the beads.
Release the nucleic acids from the beads into solution using the elution conditions specified in the protocol.
Mix thoroughly to redisperse the beads uniformly before withdrawing the required volume. Use clean equipment to minimize contamination.
The product is supplied as a dispersion in ultrapure water. Prepare the binding, washing and elution buffers and operating conditions according to your selected extraction protocol.
Store at 2–25°C as specified in the product information and reseal promptly after use. The stated shelf life is 360 days; refer to the bottle label for the production date, expiry date and any supplied requirements.
Please provide “SiO₂ hydroxyl magnetic beads + particle size + pack volume + concentration + number of packs” so that we can confirm the specification, quotation and supply arrangements.
For particle size distribution, batch test documentation or experimental compatibility information, please describe your sample type, extraction workflow and operating conditions, and confirm the documentation for the selected variant before purchasing.
Yes. Every variant on this page has a concentration of 10mg/mL. The 5mL and 10mL options indicate different pack volumes.
The table is ordered by 150, 200, 300, 400 and 500nm. For each size, the 5mL pack appears before the 10mL pack. Each variant has its own retail price.
This page lists SiO₂ hydroxyl magnetic beads dispersed in ultrapure water. Confirm and obtain the lysis, binding, washing and elution reagents separately according to your complete experimental protocol.
The supplied information specifies storage at 2–25°C and a shelf life of 360 days. Follow the production date and expiry date on the bottle label, together with the supplied instructions.
For product selection, quotations and bulk orders, please provide the particle size, pack volume, quantity and intended experimental use.
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Partial references citing our materials (from Google Scholar)
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